Product Description
Factory Supply High Quality Pharmaceutical Peptides Powder Atosiban CAS 90779-69-4
Specification of Analysis
Items |
Standards |
Results |
Appearance |
White powder |
Complies |
Identification |
By IR |
Complies |
By HPLC |
Complies |
Solubility |
Soluble in water |
Complies |
Amino Acid Composition |
±10% of theoretical |
Complies |
MS |
994.19±1.0 |
Complies |
Water Content |
≤ 5.0% |
1.54% |
Acetic Acid |
≤ 15.0% |
5.01% |
Related Substances (Test Method A) |
Any single impurity: ≤0.50% |
0.19% |
Total impurities: ≤2.00 % |
0.55% |
Related Substances (Test Method B) |
Any single mpurity: ≤0.50% |
0.13% |
Total impurities: ≤2.00 % |
0.26% |
Peptid Content |
≥ 80.0% |
91.46% |
Reference Standard |
In-house Standard |
|
|
What is Atosiban CAS 90779-69-4 ?
Atosiban was introduced in the UK as an injectable inhibitor of preterm labor, a major cause of infant morbidity and mortality. This peptidic oxytocin analog is an antagonist of the vasopressin V1a receptor and of the oxytocin receptor which is found in dramatically increased concentration in the uterine myometrium of pregnant women near term. It competitively inhibited contractions in the pregnant guinea pig uterus induced by oxytocin and vasopressin. In a multicenter, double-blind, placebo-controlled trial, treatment with atosiban caused pregnancy prolongation for up to 7 days in women with more than 28 weeks of gestation. In a comparative clinical trial, atosiban showed a comparable tocolytic action (uterine relaxant) to ritodrine but the former was significantly better tolerated, especially with regards to maternal cardiovascular side effects. In healthy volunteers, plasma levels of atosiban decreased bi-exponentially with an initial and a terminal half-life of 21 min and 1.7h respectively.
Application:
1.Atosiban is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/oxytocin receptor antagonist (VOTra).
2.Atosiban inhibits the oxytocin-mediated release of inositol trisphosphatefrom the myometrial cell membrane.
3.Atosiban is useful in improving the pregnancy outcome of in vitro fertilization-embryo transfer (IVF-ET) in patients with repeated
implantation failure (RIF). The pregnancy rate improved from zero to 43.7%.
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Packing
For Small Order:
Powder
1G-1KG/Foil Bag
5KG/Foil bag
10KG/Foil bag
25KG/Drum
Liquid
1KG/Plastic bottle
25KG/Barrel
For Big Order:
Powder
25KG/DRUM
Liquid
100KG/Barrel
200KG/Barrel
Shipping & Delivery Time
For Small Orders: 1G-25KG
By Air (Special line) or By Express --- EMS/FEDEX/UPS/DHL/***/DPD etc.
Delivery Time:
By Air (Special line) --- 15-25 Days for Door-to-Door Delivery.
By Express --- 5-7 Days for Door-to-Door Delivery.
For Large Orders: 100kg+
By Air or By Sea
Delivery Time:
By Air (Special Line) --- 15-25 Days for Door-to-Door Delivery.
By Sea: 30-45 Days for Delivery from Sea Port.
Payment
FAQ
Q1: May I get one sample before placing order?
Re: Yes, Sample are available. For normal products, samples are for free and you just need to bear the freight; For those high value products, you just need to freight and certain product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.
Q2: Which payment is available for your company?
Re: T/T, Western Union,Money Gram,Bank Transfer,Paypal or Bitcoins. You can choose the one which is convenient for you.
Q3: How and when can I get my goods after payment?
Re: For small quantity products, they will be delivered to you by international courier(DHL, FedEx, TNT etc.)
or by air. Usually it will cost 3-5 days that you can get the goods after delivery.
For large quantity products,shipping by sea is worthwhile.It will cost days to weeks to come to your destination port, which depends on where the port is.
Q4: Is there any possible to use my appointed label or package?
Re: Yes. If needed, we'd like to use label or package according to your requirement.
Q5: How can you guarantee the goods you offer is qualified?
Re: We always believe honesty and responsibility are basis of one company, so whatever products we provide for you all are qualified. We will have goods tested and provide COA before delivery for sure.
Q6:Is there any after-sales service?
Re:We promise 100% refund if it is not delivery or poor quality.